Key result
AMI hospitalizations rose significantly among young Brazilians aged 10–29 from 2015 to 2024.
Why the study?
The temporal trend of hospitalisations due to acute myocardial infarction in young people in Brazil from 2015 to 2024 was not previously analysed.
Observational (n=10,100)
Yes
Effect estimate: Coefficient 0.09
There has been a statistically significant upward trend in acute myocardial infarction hospitalisations among young adults in Brazil from 2015 to 2024, highlighting the need for targeted early prevention strategies.
May signal rising AMI burden among young Brazilians; hypothesis-generating and requires prospective confirmation before guiding prevention.
BACKGROUND: This study aimed to analyse the temporal trend of hospitalisations due to AMI in young people in Brazil, from 2015 to 2024. METHODS: This is an ecological time-series study (2015-2024), with data from the Hospital Information System, on hospitalisations due to AMI in young people, considering individuals aged between 10 and 29 years. The data were analysed using the Prais-Winsten method, with a significance level of 5%, where the temporal trend of the hospitalisations of AMI in young people was calculated. RESULTS: 10,100 AMI cases were reported, corresponding to an approximate hospitalisation rate of 1.56 cases per 100,000 inhabitants per year. From 2015 to 2024, hospitalisations for AMI among young people increased significantly (coefficient = 0.09), with the highest rises in the South (0.13) and Midwest (0.23) regions. Dividing the interval into two subperiods revealed that from 2015 to 2019, all coefficients were positive, but only the South region exhibited a statistically significant trend (coefficient = 0.07). In the next period, 2020-2024, Brazil showed an upward trend in AMI hospitalisations (coefficient = 0.15), with the Northeast (coefficient = 0.09), South (coefficient = 0.25), and Midwest (coefficient = 0.29) regions also demonstrating significant increases. CONCLUSION: The study indicates an upward trend in AMI in the young Brazilian population, reiterating the epidemiological transition, which points to the urgent need to reorient public health policies, focusing on early prevention, timely diagnosis and reducing social and racial inequalities that influence cardiovascular risk in young people.
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Santos et al. (2026) conducted an observational in Acute myocardial infarction (n=10,100). Time period (2015-2024) was evaluated on Hospitalisations due to AMI (Coefficient 0.09). Time trends from 2015 to 2024 showed a significant increase in hospitalizations for acute myocardial infarction among young Brazilians aged 10-29 (overall trend coefficient = 0.09).
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