Key result
Pulsed field ablation shows promise for para-Hisian PVCs while permitting conduction system recovery.
Why the study?
PVCs near the His-bundle pose challenges for catheter ablation due to risk of AV block and collateral injury with thermal energy sources.
Case Report
Pulsed field ablation represents a promising non-thermal strategy for para-Hisian PVCs that may minimize collateral injury to the specialized conduction system.
Answers are grounded in this paper and cite their sources.
Single-case PFA use near His bundle showed transient conduction recovery; leaves open prospective trials before clinical adoption.
Premature ventricular complexes (PVCs) originating from the vicinity of the His-bundle region represent unique challenges for catheter ablation due to the risk of atrioventricular (AV) block.1 Thermal energy sources carry the potential for collateral injury to the specialized conduction system as well as surrounding extracardiac structures. Pulsed field ablation (PFA) is a promising non-thermal ablative strategy for the treatment of atrial and ventricular arrhythmias with an enhanced safety profile driven by its dose-dependent tissue selectivity.
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Alkhunaizi et al. (2026) conducted a case report in Para-Hisian premature ventricular complexes. Pulsed field ablation (PFA) was evaluated. Pulsed field ablation is highlighted as a promising non-thermal ablative strategy for para-Hisian premature ventricular complexes, potentially allowing conduction system recovery.
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