Key result
Native-valve TAVI lowers mean aortic gradient by ~34 mmHg in late apicoaortic conduit dysfunction.
Why the study?
Apicoaortic conduit surgery was historically performed for severe aortic stenosis with hostile anatomy, but management of late conduit dysfunction remains unclear.
Case Report (n=1)
No
TAVI on the native aortic valve is a feasible and less invasive alternative to redo surgery for restoring antegrade outflow in patients with late apicoaortic conduit dysfunction.
Answers are grounded in this paper and cite their sources.
Native-valve TAVI may relieve obstruction in late apicoaortic conduit dysfunction; leaves open its role versus redo surgery pending prospective data.
Objective: Apicoaortic conduit (AAC) surgery was historically performed for patients with severe aortic stenosis and hostile aortic anatomy. We report a case in which transcatheter aortic valve implantation (TAVI) on the native aortic valve restored effective antegrade outflow in a patient with late AAC dysfunction. Case Presentation: A 71-year-old woman who had undergone coronary artery bypass grafting and AAC surgery using a mechanical valve presented with progressive dyspnea and leg edema. Echocardiography revealed severe flow acceleration at the left ventricular-side AAC anastomosis, with a peak velocity of 6.2 m/s and a mean pressure gradient of 69 mmHg, whereas no significant acceleration or mechanical valve dysfunction was observed within the conduit itself. The native aortic valve also showed severe stenosis, with a mean gradient of 42.0 mmHg and markedly reduced antegrade flow. The heart team elected to perform TAVI on the native aortic valve to restore effective antegrade outflow. Following pre-dilation, a 26-mm Evolut FX+ self-expanding valve (Medtronic, Minneapolis, MN, USA) was successfully implanted. After TAVI, the native aortic valve mean gradient decreased to 7.9 mmHg, and the effective orifice area was 1.02 cm 2 . Estimated stroke volume through the AAC pathway decreased from 163 to 78.9 mL. The patient’s symptoms improved from New York Heart Association functional class III to I. Conclusion: TAVI for the native aortic valve can restore effective antegrade outflow and serve as a less invasive alternative to redo surgery for patients with late AAC dysfunction.
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Kanda et al. (2026) conducted a case report in Late apicoaortic conduit (AAC) dysfunction and severe native aortic stenosis (n=1). Transcatheter aortic valve implantation (TAVI) was evaluated on Echocardiographic hemodynamics and symptomatic improvement. Native-valve transcatheter aortic valve implantation decreased the mean aortic gradient from 42.0 to 7.9 mmHg and improved symptoms from NYHA class III to I in a patient with late apicoaortic conduit dysfunction.
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