Key result
Symptoms including pain or discomfort in the chest, the left breast, and the superior part of the chest, as well as numbness or burning in both arms, strongly predicted the incidence of acute coronary syndrome (OR > 4, p ≤ 0.05).
Why the study?
Identifying specific prodromal cardiac symptoms can play an important role in screening people at risk of acute coronary syndrome.
Case-Control (n=337)
No
These symptoms may heighten clinical suspicion for ACS; hypothesis-generating for screening tools but requires prospective validation before practice change.
AIMS: Assessing the prodromal cardiac symptoms in patients with acute coronary syndrome (ACS) and compare them with healthy population. BACKGROUND: Identifying specific prodromal cardiac symptoms can play an important role in screening people at risk. DESIGN: A comparative study of prodromal symptoms. METHODS: In this comparison study, an 80-item checklist of prodromal symptoms was designed and completed by 337 participants in three groups (Patient group I, Patient group II and Healthy group). All participants were studied over a period of six months (from May to October 2017). SPSS-15 software was used to analyse the data. RESULTS: The symptoms of pain/discomfort in chest, pain/discomfort centred in the superior part of chest, pain/discomfort in the left breast and numbness or burning of both arms were the most important symptoms to predict ACS incidence in the two patient groups (odds ratio > 4 and p ≤ .05).
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Heidarzadeh et al. (2020) conducted a case-control in Acute Coronary Syndrome (ACS) (n=337). Specific prodromal symptoms (e.g., chest pain/discomfort, left breast pain, arm numbness/burning) vs. Absence of specific prodromal symptoms / Healthy controls was evaluated on Prediction of ACS incidence based on presence of specific prodromal symptoms (OR > 4, p=≤0.05). Symptoms including pain or discomfort in the chest, the left breast, and the superior part of the chest, as well as numbness or burning in both arms, strongly predicted the incidence of acute coronary syndrome (OR > 4, p ≤ 0.05).
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