Genetic association with bladder cancer.

temperature for 14 days following activation.3With the recently introduced alkaline glutaraldehyde formulations developments in activa- tion techniques, using modified initial pH and buffer systems, have considerably reduced the extent of glutaraldehyde polymerisation after activation.This greatly diminishes the hazard of inactivation from in-use dilution with water carry-over during sterilisation and disinfection cycles.It is recognised that in-use dilution and inactivation, rather than chemical instability, are now the major factors limiting the use life of many of the recently introduced alkaline glutaraldehyde preparations.3Although certain manufacturers recommend a 28-day life in situations of low dilution and low-to-moderate throughput, authorities in cross-infection control in the United Kingdom have ques- tioned the desirability of repeated use of disinfectant solutions.Despite improved chemical stability they are reluctant to recom- mend repeated use of a solution for more than 7-14 days.4Freedom from corrosivity has always been a desirable feature of a glutaraldehyde-based steriliser and disinfectant formulation, and is a more essential prerequisite with the increasing application to decontamination, where the solution is confronted with a wide variety of metals in equipment.