Key result
Red wine shows inconsistent effects on central hemodynamics and arterial stiffness across published studies.
Why the study?
The effects of red wine on arterial stiffness, wave reflections, and central blood pressures are poorly explored with divergent results and unclear consequences of acute and long-term intake.
Red wine effects on central pressures and stiffness remain inconclusive in observational data; leaves open any clinical or prognostic role.
Red wine is considered to reduce cardiovascular risk and decrease peripheral systolic and diastolic blood pressure. Central aortic pressures are often more sensitive clinical and prognostic factors than peripheral pressures, while arterial stiffness is an independent prognostic factor for cardiovascular events. Great efforts are being made to find natural sources of improving health. In order to clarify the mechanisms under which a widely used drink, like red wine, is affecting heart and vessels, we aimed to review the available data regarding the effects of red wine on arterial stiffness, wave reflections and central blood pressures. The effect of red wine on central hemodynamics has been poorly explored with divergent results. Possible consequences of acute and long-term intake on arterial stiffness, wave reflections and central pressures are not clear. This might make someone skeptical when suggesting the consumption of a glass of red wine, although its cardioprotective actions (when moderately consumed) are already shown from epidemiological studies.
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Karatzi et al. (2009) reported a review. Red wine was evaluated. Red wine intake effects on central hemodynamics and arterial stiffness are poorly explored with divergent results, leaving the consequences of acute and long-term consumption unclear.
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