Key result
Hyperthyroidism-induced coronary vasospasm triggers severe transmural ischemia despite normal coronary arteries.
Why the study?
Myocardial ischemia or infarction caused by coronary vasospasm associated with hyperthyroidism is rare despite common cardiac complications of hyperthyroidism.
Case Report (n=1)
No
Vasospasm should be considered in hyperthyroid chest pain; leaves open whether thyroid excess triggers coronary events.
There are many kinds of cardiac complications of hyperthyroidism such as angina pectoris, myocardial infarction, atrial fibrillation, congestive heart failure, heart block and sudden death. While angina is not uncommonly seen in association with hyperthyroidsm, it is rare that myocardial ischemia or infarction may be caused by coronary vasospasm. A 46 year-old man, who had been diagnosed with hyperthyroidism at the first admission, presented with chest pain. The serum thyroid hormone was still elevated. Serial ECGs showed significant ST elevation suggesting transmural ischemia, but coronary angiogram did not reveal any significant lesion. ECG at discharge was normalized without evidence of myocardial infartion. We report this case as an example of severe transmural ischemia with myocardial injury caused by coronary spasm associated with hyperthyroidism. (Korean Circulation J 2000;30(3):369-372)
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Jong Hyung Kim (2000) conducted a case report in Myocardial ischemia and coronary vasospasm associated with hyperthyroidism (n=1). Hyperthyroidism was evaluated. Severe transmural ischemia and myocardial injury can be caused by coronary vasospasm associated with hyperthyroidism in the absence of significant angiographic lesions.
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