Key result
Palliative VAC chemotherapy yields 6-month survival in rare infantile left ventricular rhabdomyosarcoma.
Why the study?
Primary malignant cardiac tumors are extremely rare in children, with very few pediatric cases of rhabdomyosarcoma reported in the literature.
Case Report (n=1)
No
Documents fatal course of infantile LV rhabdomyosarcoma despite palliative VAC; extends sparse literature on this rare entity.
Primary cardiac tumors are rare in children, usually consist of benign tumors like rhabdomyomas and fibromas that may spontaneously regress. Primary malignant tumors are extremely rare even in adults and very few paediatric cases were reported in literature. Rhabdomyosarcoma is a rare primary malignant tumor in children and most of the reported cases occur in right ventricle, left atrium and right atrium. We report a 15 month old child with primary rhabdomyosarcoma of left ventricle presenting in cardiac tamponade and circulatory failure.
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Maram et al. (2021) conducted a case report in Primary Cardiac Rhabdomyosarcoma (n=1). Palliative chemotherapy with VAC regimen (Vincristine, Dactinomycin, Cyclophosphamide) was evaluated on Survival. A 15-month-old boy with a rare primary cardiac rhabdomyosarcoma arising from the left ventricle underwent palliative VAC chemotherapy but succumbed to the disease six months later.
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