Key result
Hypertension is linked to ~134 mg/dl higher total cholesterol alongside adverse lipid profiles.
Why the study?
The relationship between elevated plasma lipids and hypertension in patients from Owerri Municipal was investigated to inform effective management strategies.
Case-Control (n=150)
No
Absolute Event Rate: 288% vs 154%
p-value: p=<0.05
Hypertensive patients demonstrated a significantly more atherogenic lipid profile compared to normotensive individuals, reinforcing the importance of routine lipid monitoring in hypertension management.
May warrant lipid monitoring in hypertension; leaves open causal direction and requires prospective studies.
This study was conducted in Owerri Municipal between the months of February, 2014 to March, 2015. A total of 150 fasting blood samples were collected from normal and hypertensive patients. The samples were analyzed using standard biochemical methods. The mean level of cholesterol, triglyceride, and LDL (288 +0.33, 110 + o.33 and 89 + 0.73 mg/dl) in hypertensive patients showed and significant difference when compared with those of normal subjects (154 + 2.36, 46 + 0.91 and 32 + 0. 09mg/dl) at P<0.25. The study also revealed a significant difference in the mean value of HDL-cholesterol (24 + 0.74mg/dl) in hypertensives, when compared with normal subjects (86 + 0.34mg/dll) at P< 0.25. The data suggests that elevated plasma lipids are related to hypertension and other cardiovascular diseases. Therefore, regular monitory of lipid levels in hypertensives will enhance effective management of patients.
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E. U. Nwabueze (2026) conducted a case-control in Hypertension (n=150). Hypertension vs. Normotensive controls was evaluated on Mean total cholesterol (mg/dl) (p=<0.05).
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