Key result
Novel micropulse device measures SBP ~2.5 mmHg lower than manual auscultation.
Why the study?
Current blood pressure measurement techniques only estimate values from various private clinical measurements, lacking true accuracy.
Does a novel automated micropulse blood pressure measurement device provide accurate readings compared to gold standard manual auscultation in healthy subjects?
Observational (n=32)
No
Does a novel automated micropulse blood pressure measurement device provide accurate readings compared to gold standard manual auscultation in healthy subjects?
Mean Difference: -2.5
p-value: p=0.00012
The first practical automatic micropulse blood pressure measurement device demonstrated high accuracy compared to manual auscultation, successfully fulfilling international standards for automated blood pressure devices without requiring proprietary oscillometric estimation.
True accuracy for blood pressure measurement devices is required, but current techniques only estimate, deriving measurements from various private sets of clinical measurements. We previously reported a new technique that detects micropulse arterial opening, present only for beats between systole and diastole, enabling direct determination of systolic and diastolic blood pressures (SBP & DBP). We have now developed a first automated device using our technique and have compared its accuracy with current gold standard auscultatory measurements in 32 subjects. The differences between our novel device and simultaneous auscultatory measurements were for SBP -2.5 ± 3.1 mmHg, and for DBP -1.0 ± 1.2 mmHg (mean ± standard deviation SD). Results were well within the clinical international standard's limits of 5 ± 8 mmHg.
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Murray et al. (2026) conducted an observational in Healthy subjects (n=32). Automated micropulse blood pressure measurement device vs. Simultaneous manual auscultation was evaluated on Difference between device and simultaneous auscultatory measurements for systolic blood pressure (MD -2.5 ± 3.1 mmHg, p=0.00012). The novel automated micropulse device accurately measured blood pressure, with a mean difference of -2.5 mmHg for SBP compared to manual auscultation.
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