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“It has long been known that symptomatic VHD carries a poor prognosis, but contemporary research shows that even asymptomatic untreated hemodynamically significant VHD carries a high risk of adverse outcomes. This is especially true for the two most prevalent forms of VHD, aortic stenosis (AS) and mitral regurgitation (MR).”
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Banovic et al. (2026) studied this question.
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