Residential treatment for substance use disorders (SUDs) is widely used, but outcome evidence remains limited by inconsistent measurement and insufficient attention to multidomain recovery. 158 treatment episodes were analyzed from a 28-day phased residential program in the United Kingdom. Admission and pre-discharge measures included the Patient Health Questionnaire (PHQ-9), Generalized Anxiety Disorder scale (GAD-7), Brief Craving Scale (BCS) and WHOQOL-BREF psychological domain. Change was estimated using Cohen’s dz with 95% confidence intervals. Clinically meaningful change was assessed using reliable change indices and study-defined improvement thresholds. Temporal stability was also examined. Large to very large improvements were observed across all domains: depression (dz = 2.14), anxiety (dz = 1.90), craving (dz = 1.43) and psychological quality of life (dz = 1.46) (all p <.001). Reliable improvement occurred in 61.4%–82.3% of episodes. Study-defined improvement thresholds were met in at least three of four domains in 86.1% of cases, and 57.0% improved across all four domains. Severity distributions shifted markedly toward minimal or mild ranges by discharge, with no evidence of performance drift. A phased residential model was associated with substantial multidomain improvement in routine care, supporting structured treatment sequencing and multidomain outcome assessment in addiction recovery.
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Lomas et al. (2026) studied this question.
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