Key result
Inadequate sleep linked to ~10% higher hypertension risk in women.
Why the study?
The association between sleep duration and the development of hypertension in women was not well established.
Does inadequate sleep duration increase the risk of developing hypertension in women?
Meta-Analysis
Does inadequate sleep duration increase the risk of developing hypertension in women?
Insufficient sleep duration, but not long sleep duration, is associated with a significantly higher risk of developing hypertension in women.
Short sleep may raise women's hypertension risk; leaves open causality and need for intervention trials.
This study examined the association between females' sleep duration and the development of hypertension (HTN). Searches were conducted in Embase, PubMed, Cochrane Library, Web of Science, CNKI, VIP, and Wanfang databases up to March 15, 2024. Using RR as the effect measure, the combined RR and 95% CI were calculated using Stata 15.0. A total of 10 articles, comprising 12 cohort studies, were included in the meta-analysis. Inadequate sleep duration is associated with HTN in women (RR: 1.10, 95% CI: 1.06-1.13, p <0.001). However, long sleep duration was not associated with HTN in women (RR: 1.00, 95% CI: 0.96-1.05, p = 0.958). Short- and long-sleep duration groups showed no publication bias. Subgroup and meta-regression analyses indicated that age and variation in the operational definition of sleep duration were the principal sources of heterogeneity. In age-stratified analysis, both <50 years (RR = 1.19, 95% CI: 1.11-1.28, p <0.001) and ≥50 years (RR = 1.06, 95% CI: 1.00-1.12, p = 0.036) showed increased HTN risk among women with short sleep duration. The dose-response association was L-shaped; using 4 hours/day as the reference, the lowest risk was observed at approximately 7.5 hours/day. For women, insufficient sleep duration is linked to a higher risk of developing HTN.
No takes yet. Share an insight, caveat, or question.
Bai et al. (2026) conducted a meta-analysis in Hypertension. Inadequate sleep duration vs. Adequate sleep duration was evaluated on Development of hypertension (RR 1.10, 95% CI 1.06-1.13, p=<0.001). Inadequate sleep duration is associated with a higher risk of developing hypertension in women (RR 1.10; 95% CI 1.06-1.13; p<0.001), whereas long sleep duration showed no significant association.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: