Key result
Higher SDI is linked to steeper global rheumatic heart disease mortality declines despite slight prevalence gains.
Why the study?
Significant regional disparities and limited declines in rheumatic heart disease burden were observed globally from 1990 to 2021, necessitating targeted prevention and control strategies.
Observational
Yes
p-value: p=<0.001
Despite steady declines in global mortality from rheumatic heart disease between 1990 and 2021, its prevalence slightly increased, revealing marked regional disparities heavily influenced by socio-demographic index (SDI).
<0.001).The EAPCs of ASDR and ASPR were associated with both baseline burden in 1990 and SDI in 2021.Countries with higher SDI experienced more substantial declines in RHD burden.However,the declines were limited in areas with high baseline prevalence,and some regions even showed upward trends. Conclusions Between 1990 and 2021,although the global mortality of RHD steadily declined,the prevalence slightly increased,with females and older adults bearing a disproportionate burden.Significant regional disparities in disease burden were observed.More pronounced declines occurred in countries with a high SDI,whereas some low-SDI and high-baseline-burden regions showed little or no decline,which suggested the need for sustained and targeted comprehensive prevention and control strategies in key areas.
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Zhuo et al. (2026) conducted an observational in Rheumatic Heart Disease. Sociodemographic Index (SDI) and Time was evaluated on Rheumatic Heart Disease burden (ASDR and ASPR) (p=<0.001). Higher Sociodemographic Index (SDI) was associated with more substantial declines in global rheumatic heart disease mortality from 1990 to 2021, though prevalence slightly increased overall (P<0.001).
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