Key result
HF congestion extends beyond weight and edema, requiring integrated vascular and interstitial assessment.
Why the study?
Lower-limb oedema and weight gain imperfectly reflect the complex pathological process of congestion in heart failure, necessitating an integrated assessment approach.
An integrated approach to assessing congestion in heart failure is necessary, as traditional signs like edema and weight gain imperfectly reflect complex vascular and interstitial changes.
Answers are grounded in this paper and cite their sources.
Oedema and weight gain imperfectly reflect HF congestion; leaves open validation of integrated vascular-interstitial monitoring.
Lower-limb oedema and weight gain remain key components in the assessment of congestion in heart failure and continue to guide clinical decision-making. However, they only imperfectly reflect a complex pathological process involving interactions between the vascular and interstitial compartments, venous capacitance, and lymphatic drainage. Congestion extends beyond simple tissue fluid accumulation or weight gain and includes changes in vascular pressures and volumes that may be dissociated from one another and difficult to detect clinically. This dissociation may lead to diagnostic bias and overinterpretation of visible signs. An integrated approach to congestion therefore appears necessary to improve patient assessment and management.
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Sanson et al. (2026) conducted a review in Heart failure. Congestion in heart failure extends beyond simple weight gain or edema and requires an integrated clinical approach to account for complex vascular and interstitial compartment interactions.
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