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Background: Primary mesenchymal chondrosarcoma is a rare malignant neoplasm originating from bone and soft tissue commonly involving maxilla and mandible, but can also involve ribs, pelvis, femur, and spine. Case report: 16 years-old-female presented with weakness and paresthesia of lower limbs since 15 days with difficulty in walking. CT scan showed pre and paravertebral soft tissue density lesion extending from D8 to D12 vertebral body levels. MRI showed heterogenous lesion with hypo and hyperintense areas in T1W1 and hyperintense on T2. Tumor is excised and on histopathological examination revealed the features of mesenchymal chondrosarcoma. Conclusion: Mesenchymal chondrosarcoma is a rare malignant mesenchymal tumor located in bone, intracranial sites or soft tissue with non-specific findings on imaging. Histopathology and additional immunohistochemistry is gold standard for diagnosis.
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Shanthi et al. (2026) studied this question.
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