Ecocardiografía bidimensional con speckle tracking en Miocardiopatía Diabética subclínica: revisión sistemática cualitativa.

Q: What is the clinical evidence from this study?

Study design: Systematic Review. Population: Subclinical Diabetic Cardiomyopathy in Type 2 Diabetes Mellitus (n=2005). Intervention: Type 2 Diabetes Mellitus vs. Healthy controls. Primary outcome: Myocardial deformation (Global Longitudinal Strain, GLS).

Q: What does this research mean for the field?

Patients with type 2 diabetes mellitus have significantly reduced left ventricular global longitudinal strain compared to healthy controls, allowing early detection of subclinical multi-chamber myocardial dysfunction before conventional echocardiographic parameters change. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

Jorge Jones O.; Diego Villarroel E.; Adolfo Lang B.; Franco Tortorolo B.; Tamara Sáez Gutiérrez; Rienzi Díaz-Navarro

doi:10.4067/s0718-85602026000200107

August 1, 2026Revista chilena de cardiologíaOpen Access

Ecocardiografía bidimensional con speckle tracking en Miocardiopatía Diabética subclínica: revisión sistemática cualitativa.

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Why the study?

Early diagnosis of subclinical diabetic cardiomyopathy in type 2 diabetes mellitus patients is challenging and requires sensitive imaging techniques.

Study Design

Type

Systematic Review (n=2,005)

PICO

P

Population

2,005 adults across 20 studies, comprising 1,038 patients with uncomplicated type 2 diabetes mellitus and 967 healthy controls, evaluated for subclinical myocardial dysfunction using 2D-STE.

E

Exposure / Comparator

Type 2 Diabetes Mellitus vs Healthy controls

O

Primary Outcome

Myocardial deformation (Global Longitudinal Strain, GLS)

Limitations

Heterogeneity of inclusion and exclusion criteria across the included studies
Differences in the reporting of conventional and strain echocardiographic parameters, especially for the right ventricle and left atrium
Predominantly observational and cross-sectional study designs
Wide variability in the duration of type 2 diabetes mellitus among patients
Significant variability in myocardial deformation values (GLS) depending on the analysis software vendor, precluding a reliable meta-analysis

Abstract

conflictos de interés.

Discussion

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Cite This Study

O. et al. (2026) conducted a systematic review in Subclinical Diabetic Cardiomyopathy in Type 2 Diabetes Mellitus (n=2,005). Type 2 Diabetes Mellitus vs. Healthy controls was evaluated on Myocardial deformation (Global Longitudinal Strain, GLS).

synapsesocial.com/papers/6ad0fd063afa093ea9ad015b https://doi.org/10.4067/s0718-85602026000200107

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Ecocardiografía bidimensional con speckle tracking en Miocardiopatía Diabética subclínica: revisión sistemática cualitativa.

Study Design

PICO

Limitations

Abstract

Discussion

Cite This Study

Ecocardiografía bidimensional con speckle tracking en Miocardiopatía Diabética subclínica: revisión sistemática cualitativa.

Study Design

PICO

Limitations

Abstract

Discussion

Cite This Study

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