Key result
MeDeA matches black-box ECG diagnostic accuracy while improving attribution faithfulness, achieving a ~0.78 macro-F1 score.
Why the study?
Many high-performing deep learning models for ECG classification provide limited class-specific interpretability, motivating development of intrinsically interpretable methods.
Does the MeDeA framework maintain diagnostic performance while improving interpretability compared to black-box baselines for ECG classification?
Does the MeDeA framework maintain diagnostic performance while improving interpretability compared to black-box baselines for ECG classification?
The MeDeA framework demonstrates that deep learning models for ECG interpretation can achieve high accuracy (macro-F1 0.775) while providing built-in, disease-specific interpretability.
MeDeA may improve clinician trust in ECG DL outputs; leaves open whether attention maps enhance diagnostic accuracy or outcomes.
Deep learning has achieved strong performance on electrocardiogram (ECG) classification, yet many high-performing models still provide limited class-specific interpretability. We present MeDeA (multi-disease decompositional attention), a decomposable attention framework for intrinsically interpretable ECG diagnosis. The central idea is to combine a shared 1D backbone with disease-specific attention heads so that each predicted condition is associated with a dedicated explanatory pathway instead of relying solely on post-hoc attribution. We further describe a multi-query formulation, termed multi-query attention head (MQAH), in which each disease head contains a small set of global learnable queries to capture complementary morphological patterns. Experiments on the PTB-XL dataset show that MeDeA achieves a macro-F1 score of 0.775, matching strong black-box baselines while improving attribution faithfulness. We also report efficiency metrics including parameter count, weight footprint, and forward latency. Finally, we discuss limitations related to retrospective public datasets, shifts across hospitals and devices, sampling-rate mismatch, and annotation quality.
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GE et al. (2026) studied ECG diagnosis. MeDeA (multi-disease decompositional attention) framework vs. black-box baselines was evaluated on macro-F1 score. MeDeA achieved a macro-F1 score of 0.775 on the PTB-XL dataset, matching strong black-box baselines while improving attribution faithfulness.
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