Key result
Lactate levels as a prognostic marker in complete atrioventricular block require careful interpretation due to the biomarker's nonspecific nature and the heterogeneity of composite clinical endpoints.
Why the study?
Do admission and follow-up lactate levels predict adverse in-hospital clinical outcomes in patients with complete atrioventricular block?
Do admission and follow-up lactate levels predict adverse in-hospital clinical outcomes in patients with complete atrioventricular block?
This letter emphasizes the need for cautious interpretation of lactate's prognostic value in complete AV block due to its non-specific nature and the heterogeneity of composite endpoints.
article entitled "Assessment of Lactate Levels as Prognostic and Predictive Markers in Patients with Complete Atrioventricular Block" by Cengiz et al. 1 with great interest. I congratulate the authors for addressing an important topic with limited existing literature by investigating the prognostic value of lactate levels in patients with complete atrioventricular block. The association of admission and follow-up lactate levels with adverse in-hospital clinical outcomes is of clinical interest and may provide useful information for risk stratification and future studies. Nevertheless, discussion of certain points would be beneficial for a more comprehensive evaluation of the study findings
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Gazi Çapar (2026) conducted a letter in Complete atrioventricular block. Lactate levels was evaluated on Composite of acute kidney injury, cardiac mortality, and need for temporary pacemaker implantation. Lactate levels as a prognostic marker in complete atrioventricular block require careful interpretation due to the biomarker's nonspecific nature and the heterogeneity of composite clinical endpoints.
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