Key result
TAVR in bicuspid aortic valve stenosis shows high device success and favorable procedural safety.
Why the study?
Randomized clinical trial data on TAVR use in bicuspid aortic valve anatomy are lacking due to exclusion from pivotal studies.
Is transcatheter aortic valve replacement safe and effective in patients with bicuspid aortic valve stenosis?
Is transcatheter aortic valve replacement safe and effective in patients with bicuspid aortic valve stenosis?
This review highlights that despite exclusion from early pivotal trials, emerging evidence suggests TAVR is a safe and increasingly successful option for patients with bicuspid aortic valve stenosis.
The paucity of data from randomized clinical trials regarding the use of transcatheter aortic valve replacement (TAVR) in bicuspid aortic valve anatomy due to exclusion from pivotal studies continues to present a challenge as we expand TAVR to patients with BAV. This article discusses the important anatomic and clinical considerations in the selection and management of BAV patients with TAVR and reviews the emerging evidence, which increasingly suggests this procedure is safe, device success is excellent, and procedural outcomes are much improved.
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Kolkailah et al. (2026) conducted a review in Bicuspid aortic valve stenosis. Transcatheter aortic valve replacement (TAVR) was evaluated. Transcatheter aortic valve replacement for bicuspid aortic valve stenosis is increasingly suggested by emerging evidence to be safe, with excellent device success and improved procedural outcomes.
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