Procalcitonin-guided antibiotic discontinuation after ADAPT-Sepsis: a national survey of current practice and readiness for implementation

Procalcitonin (PCT)-guided antibiotic discontinuation is increasingly supported by evidence, but current UK practice remains uncertain. We conducted a national survey of acute healthcare staff to describe current PCT use and organisational readiness for implementation of PCT-guided antibiotic discontinuation. Eighty-six responses were analysed. PCT was mostly measured occasionally in selected patients, while 28% of respondents reported rarely or never measuring PCT. Nearly half wished to increase their use of PCT-guided antibiotic discontinuation, while almost a third wanted further information before making practice changes. Organisational readiness scores were generally favourable. Ongoing implementation may be supported by national guidance, local protocols and education.