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A goldfish ( Carassius auratus ) from a pet store was presented with a nodular lesion on the dorsal cranial region. The fish exhibited normal swimming behaviour and appetite. Clinical evaluation, haematology analysis, and radiography confirmed a superficial cutaneous mass without internal organ involvement. A surgical approach was performed under eugenol anaesthesia, with local lidocaine for pain management. Histopathology, including Masson's trichrome staining and immunohistochemistry (vimentin, CD57 and S100), confirmed a diagnosis of cutaneous neurofibroma. Postoperative care included topical Aloe vera , oral oxytetracycline and water treatment with methylene blue and salt. The fish recovered successfully and was returned to the pet store.
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Duarte-Rodríguez et al. (2026) studied this question.
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