Key result
Severe LVOT obstruction with ~100 mmHg gradient resolves completely within three weeks in Tako-Tsubo syndrome.
Why the study?
Transient left ventricular outflow tract obstruction in Tako-Tsubo syndrome has been reported but its features and clinical implications require further description.
Case Report (n=1)
No
This is a clinical case of an 83-years-old woman referred to our hospital for the occurrence of chest pain and syncope, related to an intense emotional stress in the previous three months. At admission, the electrocardiogram showed S-T segment elevation from V1-V3 and deep inversion of the T-wave in V4-V6, and an increase in troponin I level (6.4 ng/mL). Echocardiogram demonstrated midapical segment akinesia with left ventricular dysfunction. Basal segments were hypercontractile and there was evidence of left ventricular outflow tract (LVOT) obstruction with an end-systolic peak gradient of 99 mmHg. Regression of the LVOT obstruction was detected at third day. Three weeks after admission a serial two-dimensional echocardiography and nuclear medicine studies showed a complete regression of the left ventricular wall motion abnormalities with an improvement of systolic function.
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Espinola-Zavaleta et al. (2017) conducted a case report in Tako-Tsubo Syndrome (n=1). Tako-Tsubo syndrome was evaluated on Regression of left ventricular outflow tract obstruction and recovery of systolic function. An 83-year-old woman with Tako-Tsubo syndrome developed severe transient left ventricular outflow tract obstruction with a peak gradient of 99 mmHg that completely resolved within three weeks.
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