Key result
Individualized therapy with antithrombotics and thrombolytics may restore patency and completely normalize neonatal myocardial function.
Why the study?
Management strategies for neonatal myocardial infarction lack evidence-based guidelines and require individualized treatment approaches.
Case Report
May support individualized neonatal MI management; hypothesis-generating for adult myocardial repair targets.
Due to the lack of evidence-based guidelines, management strategies for neonatal MI should be individualized and administered largely at the discretion of responsible treating teams. Supportive care with a focus on preserving adequate circulation and antithrombotic therapy with a view to restoring vascular patency are the mainstays of treatment. Thrombolytic therapy of neonatal MI includes a chance to completely restore myocardial function. Understanding the resilience of the neonatal heart and mechanism of cardiac cell repair in neonates may spark novel treatment strategies for severe MI in the large number of affected individuals in an aging population.
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Werner Streif (2017) conducted a case report in Neonatal myocardial infarction. Supportive care, antithrombotic therapy, and thrombolytic therapy was evaluated. Individualized management of neonatal myocardial infarction using supportive care, antithrombotic, and thrombolytic therapies may restore vascular patency and completely restore myocardial function.
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