Key result
Immunosuppressive therapy resolves lupus-associated complete heart block to first-degree AV block in ~10 days.
Why the study?
Complete heart block is a rare but serious cardiac complication of systemic lupus erythematosus that may be asymptomatic and under-recognized.
Case Report (n=1)
No
This case illustrates that high-grade atrioventricular block can manifest asymptomatically in active systemic lupus erythematosus and may be fully reversed with prompt medical immunosuppression without requiring permanent pacing.
Suggests reversibility of asymptomatic complete heart block in active SLE with immunosuppression; leaves open the role of baseline ECG screening.
Complete heart block is a rare but serious cardiac complication of systemic lupus erythematosus.Most reported cases present with symptoms such as syncope.In this report, we describe the case of a 33-year-old woman with systemic lupus erythematosus who was diagnosed with asymptomatic Complete heart block.This case highlights the importance of proactive cardiac evaluation, including a baseline electrocardiogram, in systemic lupus erythematosus patients to detect clinically silent conduction defects that may carry a risk of sudden cardiac death.
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Sok et al. (2026) conducted a case report in Systemic Lupus Erythematosus with Complete Heart Block (n=1). Glucocorticoids and immunosuppressive therapy was evaluated on Resolution of complete heart block. Asymptomatic complete heart block in a 33-year-old woman with active systemic lupus erythematosus resolved to first-degree AV block following 10 days of glucocorticoid and immunosuppressive therapy.
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