Why the study?
Conventional echocardiographic measurements of ventricular function are difficult to apply in single ventricle physiology due to unique ventricular geometry, and objective echocardiographic indices are lacking.
Cross-Sectional (n=17)
Single-blind
No
Answers are grounded in this paper and cite their sources.
Strain analysis should account for ventricular dominance; leaves open utility for guiding interventions in single-ventricle patients.
We made a frame by frame analysis of the left ventricular cineangiogram to quantitate normal regional left ventricular function. Two different methods were used: contraction of the left ventricle towards a fixed point at the center of its long axis, and a pattern of contraction normal to the outline of the ventricle. Each method was used with and without correction for rotation and translational movement during systole. Left ventricular contraction and relaxation were represented graphically on a three-dimensional perspective plot and also using contour mapping techniques. The normal values and standard deviation were calculated for the extent, velocity and time course of ventricular contraction and relaxation in each region of the ventricle. The study provided a graphic visual display of the regional contractile pattern of the normal ventricle.
No takes yet. Share an insight, caveat, or question.
Sapoznikov et al. (2008) conducted a cross-sectional in Single ventricle physiology status post Fontan palliation (n=17). Speckle tracking echocardiography (STE) myocardial deformation measures vs. Invasive pressure-volume loop (PVL) analysis was evaluated on Correlation between STE measures of deformation and PVL measures of ventricular function.
Synapse has enriched 10 related papers. Consider them for comparative context: