Wound care for Stevens-Johnson syndrome and toxic epidermal necrolysis

To the Editor: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are acute and life-threatening drug reactions characterized by extensive mucocutaneous exfoliation. SJS and TEN occur rarely, with an annual incidence of 1.2 to 9.2 and 0.4 to 1.9 per million, respectively.1,2 Wound care for SJS and/or TEN mirrors local trends in burn management, as current guidelines lack strong evidence for these pathologic processes.3-5 The aim of this review is to assess the effects of dressings used in the wound care in patients with SJS and/or TEN and present evidence rated according to the Strength of Recommendation Taxonomy criteria that will aid clinicians in determining the best approach to wound care for their patients with SJS and/or TEN.