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January 1, 1982Journal of Pharmacobio-DynamicsOpen Access

Inhibitors of poly(adenosine diphosphate ribose) polymerase potentiate the antitumor activity of bleomycin against Ehrlich ascites carcinoma.

Hisae Kawamitsu Masanao Miwa Yuko Tanaka Hiromi Sakamoto Masaaki Terada Akio Hoshi Takashi Sügimura

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Abstract

m-Aminobenzamide and benzamide, which are potent inhibitors of poly (adenosine diphosphate ribose) polymerase and have no antitumor activity themselves, potentiated the antitumor activity of bleomycin against Ehrlich ascites carcinoma in vivo.

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Kawamitsu et al. (1982) studied this question.

synapsesocial.com/papers/6adb2d86a8ca1673cc236a15 https://doi.org/10.1248/bpb1978.5.900

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