Implications of Sustained Monomorphic Ventricular Tachycardia Associated with Myocardial Injury

Brief Reports15 January 1990Implications of Sustained Monomorphic Ventricular Tachycardia Associated with Myocardial InjuryAlan Woelfel, MD, David H. W. Wohns, MD, James R. Foster, MDAlan Woelfel, MDSearch for more papers by this author, David H. W. Wohns, MDSearch for more papers by this author, James R. Foster, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-112-2-141 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptElevations of serum creatine kinase indicative of myocardial injury may be detected occasionally in patients who present with sustained monomorphic ventricular tachycardia. However, the implications of this finding with respect to subsequent susceptibility to ventricular tachycardia and the need for chronic antiarrhythmic therapy are uncertain. If ventricular tachycardia occurs only as a transient consequence of the acute phase of myocardial infarction, then long-term antiarrhythmic therapy is unnecessary, as is the case for patients who have ventricular fibrillation within the first 24 hours after acute infarction (1, 2). Alternatively, if ventricular tachycardia arises from a stable, pre-existing arrhythmogenic substrate, then recurrent...References1. CobbHallstromWeaverCopassHaynes LAWMR. Clinical predictors and characteristics of the sudden cardiac death syndrome. In: The Proceedings of the USA/USSR First Joint Symposium on Sudden Death. Bethesda, Maryland: Department of Health, Education, and Welfare, 1978: 99-116. Google Scholar2. MyerburgKesslerZamanCondeCastellanos RKLCA. Survivors of prehospital cardiac arrest. JAMA. 1982;247:1483-90. CrossrefGoogle Scholar3. MarchlinskiWaxmanShawEzriJosephson FHLMM. Electrophysiologic study for ventricular arrhythmia: effect on total and myocardial-specific creatine kinase activity. Am J Cardiol. 1982;50:1061-5. CrossrefMedlineGoogle Scholar4. EhsaniEwySobel AGB. Effects of electrical countershock on serum creatine Phosphokinase (CPK) isoenzyme activity. Am J Cardiol. 1976;37:12-8. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: From the University of North Carolina School of Medicine, Chapel Hill, North Carolina. For current author addresses, see end of text. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byManagement of Ventricular Arrhythmias in Heart FailureSustained ventricular tachycardia as a marker of inadequate myocardial perfusion during the acute phase of myocardial infarction 15 January 1990Volume 112, Issue 2Page: 141-143KeywordsCreatine kinaseInfarctionMyocardial infarctionVentricular fibrillationVentricular tachycardia Issue Published: 15 January 1990 PDF downloadLoading ...