Key result
Device-measured 24-h movement behaviors were not significantly associated with aortic or carotid IMT in young adults (30-min reallocation from sedentary behavior to LPA: MD -0.006 mm).
Why the study?
The combined associations of 24-h movement behaviors—light physical activity, moderate-to-vigorous physical activity, sedentary behavior, and sleep—with arterial intima-media thickness, especially aortic intima-media thickness, had not been previously studied in young adults.
Do device-measured 24-hour movement behaviors and theoretical time reallocations between sleep, sedentary behavior, and physical activity associate with aortic and carotid intima-media thickness in healthy young adults?
Cross-Sectional (n=327)
No
Do device-measured 24-hour movement behaviors and theoretical time reallocations between sleep, sedentary behavior, and physical activity associate with aortic and carotid intima-media thickness in healthy young adults?
Mean Difference: -0.006 (95% CI -0.018–0.006)
In apparently healthy and active young adults aged 26 years, device-measured 24-hour movement behaviors (sleep, sedentary behavior, light physical activity, and moderate-to-vigorous physical activity) were not significantly associated with preclinical atherosclerosis as measured by aortic or carotid intima-media thickness.
Combined 24-h behaviors may link to aortic IMT; leaves open utility for early cardiometabolic risk detection versus carotid measures.
Physical activity, including light physical activity (LPA) and moderate-to-vigorous physical activity (MVPA), sedentary behavior (SED), and sleep, often referred to as "24-h movement behaviors", are modifiable behaviors that may be associated with arterial intima-media thickness (IMT). However, their combined associations with arterial IMT, especially aortic IMT, where cardiometabolic risk burden may be reflected at an earlier age, have not been studied before. This study examined how 24-h movement behaviors associate with aortic and carotid IMT among young adults. Participants (n = 327) were healthy young adults (mean age 26.1 years, SD 0.2) from the Special Turku Coronary Risk Factor Intervention Project (STRIP). 24-h movement behaviors were measured using a wrist-worn accelerometer for 1 week. Aortic and carotid IMT were measured with ultrasonography. Associations between 24-h movement behaviors and aortic and carotid IMT were analyzed using compositional data analysis and compositional isotemporal substitution analysis, adjusting for sex, education, smoking, and distribution of dietary fats. Descriptive model-based estimations indicated lower aortic IMT values for compositions with a higher proportion of LPA. However, theoretical time reallocations between LPA and other behaviors did not indicate significant differences in aortic IMT (e.g., 30 min from sleep to LPA, -0.005 mm [95% CI -0.020-0.010 mm], from SED to LPA, -0.006 mm [95% CI -0.018-0.006], and from MVPA to LPA, -0.008 mm [95% CI -0.038-0.021]). No associations were found for carotid IMT either. No apparent associations were observed between 24-h movement behaviors and arterial IMT among young adults.
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Suorsa et al. (2026) conducted a cross-sectional in Subclinical atherosclerosis / vascular health in healthy young adults (n=327). Device-measured 24-hour movement behaviors (sleep, sedentary behavior, light physical activity, and moderate-to-vigorous physical activity) vs. Theoretical 30-minute isotemporal time reallocations between movement behaviors (e.g., sedentary behavior to light physical activity) was evaluated on Aortic intima-media thickness (IMT) difference with 30-minute reallocation from sedentary behavior to light physical activity (MD -0.006 mm, 95% CI -0.018 to 0.006). Device-measured 24-h movement behaviors were not significantly associated with aortic or carotid IMT in young adults (30-min reallocation from sedentary behavior to LPA: MD -0.006 mm).
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