Key result
Isolated elevated supine BP links to progressively greater post-exercise BP rise with advancing age.
Why the study?
Elevated supine BP despite normal seated BP has generated increased interest, prompting an evaluation of whether increasing age is associated with a greater BP rise post mild exercise in subjects with normal seated and elevated supine BP compared with those having both normal seated and supine BP.
Does elevated supine blood pressure despite normal seated blood pressure lead to a greater blood pressure rise post mild exercise across increasing age decades in asymptomatic unmedicated individuals?
Cross-Sectional (n=2,320)
Does elevated supine blood pressure despite normal seated blood pressure lead to a greater blood pressure rise post mild exercise across increasing age decades in asymptomatic unmedicated individuals?
Answers are grounded in this paper and cite their sources.
Asymptomatic individuals with normal seated blood pressure but elevated supine blood pressure exhibit a progressively greater blood pressure rise following mild exercise with advancing age and have increased structural and functional abnormalities.
Background Elevated supine blood pressure (BP) despite normal seated BP is with increased interest in recent studies. Purpose The purpose of this study is to assess whether increasing age is associated with greater BP rise post mild exercise between subjects with normal seated and supine BP versus those with normal seated and elevated supine BP. Methods A total of 2320 asymptomatic subjects were screened for cardiovascular risk utilizing the Early Cardiovascular Disease Risk Scoring System (ECVDRS), also called Rasmussen Risk Score which has been previously reported. In summary, the ECVDRS incorporates 7 vascular tests and 3 cardiac tests, including BP rise (<3 0mmHg) post mild exercise. These 2320 subjects were analyzed with both seated and supine BP measurements. The BP measurements were classified into the latest standard American Heart Association (AHA) guidelines. These subjects were further separated into 1223 who were not on any medications. The 1223 subjects were grouped into BP measurements with normal seated and supine compared to normal seated and abnormal supine BP. The 1223 subjects were grouped by age, 50-59, 60-69, 70-79 years, in Groups A, B and C Respectively. Results See Tables. Conclusions In normotensive seated and supine subjects, BP-rise post mild exercise becomes more pronounced with each increasing decade. BP-rise post mild exercise increases progressively with advanced age in subjects with normotensive seated and elevated supine BP. Elevated supine BP leads to more elevated BP-rise post exercise compared to normal supine BP. Elevated supine BP is associated with increased structural and functional abnormalities. According to our data, most subjects with normal seated and elevated supine BP correlated with increased structural and functional abnormalities. Time to change the guidelines.20260228-ESC2026-Abstract2-Table-Smaller
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Spahiu et al. (2026) conducted a cross-sectional in Elevated supine blood pressure despite normal seated blood pressure (n=2,320). Normal seated and elevated supine blood pressure across age decades (50-59, 60-69, 70-79 years) vs. Normal seated and normal supine blood pressure was evaluated on Blood pressure rise post mild exercise and cardiovascular structural and functional abnormalities. Elevated supine BP with normal seated BP in 1,223 unmedicated adults aged 50-79 years led to progressively greater post-exercise BP rise with each decade vs normal supine BP.
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