Key result
Non-dipping and morning surge patterns link to worsening carotid strain despite controlled office BP.
Why the study?
Non-dipper and morning surge hypertension are associated with higher cardiovascular event rates, motivating evaluation of carotid artery circumferential mechanics after adequate office blood pressure control in never-treated hypertensive patients.
Does a non-dipper or morning surge blood pressure pattern result in deteriorated common carotid artery circumferential mechanics in newly diagnosed hypertensive patients even after 1 year of adequate office blood pressure control?
Cohort (n=147)
Does a non-dipper or morning surge blood pressure pattern result in deteriorated common carotid artery circumferential mechanics in newly diagnosed hypertensive patients even after 1 year of adequate office blood pressure control?
Newly diagnosed hypertensive patients with non-dipping or morning surge blood pressure patterns exhibit persistent deterioration in common carotid artery circumferential strain even after 1 year of adequate office blood pressure control.
Answers are grounded in this paper and cite their sources.
Non-dipping may signal progressive carotid stiffness despite office BP control; hypothesis-generating for nocturnal BP targeting before practice change.
Background Non-dippers and morning surge of hypertension are known to have poor prognosis due to higher cardiovascular events. We evaluated the circumferential mechanics of carotid artery after the adequate control of the office blood pressure in the setting of never treated hypertensive patients according to the night-time dropping of blood pressure. Methods The patients diagnosed as hypertension for the first time underwent 24-hour ambulatory blood pressure monitoring, carotid ultrasound. Carotid ultrasound then rechecked after 1 year in the subjects of adequate office blood pressure control. Images of common carotid arteries stored digitally as rawDICOM format were transferred to the workstation for off-line analysis. Results 79 dippers (53.7 %) and 68 non-dippers (46.3 %) were enrolled for the analysis. Circumferential strain and strain rate showed significant differences at initial evaluation. (table). The values of them were also deteriorated even after adequate blood pressure control. When compared by quartile according to the degree of morning surges, there was a significant difference only in the circumferential strain after 1 year. Conclusion The deterioration of circumferential strain measured from common carotid artery from the very early stage of hypertension and after office blood pressure control in subjects lost diurnal blood pressure changes may explain the poorer outcomesCarotid Artery Strain
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C S Park (2026) conducted a cohort in Hypertension (n=147). Non-dipper status or morning surge of hypertension vs. Dipper status or lower quartiles of morning surge was evaluated on Circumferential strain and strain rate of the common carotid artery. Non-dipping and morning surge in hypertension (46.3% non-dippers vs 53.7% dippers) showed deteriorated carotid circumferential strain at 1 year even after adequate office blood pressure control.
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