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Fritz et al. 1 1. Fritz, A.J. ∙ Greenyer, H. ∙ Dillac, L. ... Acute degron-mediated RUNX1 loss epigenetically reprograms enhancers associated with epithelial destabilization and initiation of cancer hallmarks Cell Rep. 2026; 45 , 118129 Full Text Full Text (PDF) Scopus (0) PubMed Google Scholar use acute RUNX1 degradation to reveal how mammary epithelial cells maintain their state. RUNX1 links enhancer-centered control of epithelial identity with promoter-centered control of DNA-damage responsiveness.
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Miyata et al. (2026) studied this question.
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