Key result
Acute PE manifests with marked D-dimer elevation, sinus tachycardia, and widespread inferolateral T-wave inversions.
Case Report (n=1)
No
This case report highlights the classic ECG findings of right ventricular strain and diagnostic utility of D-dimer and CTPA in a high-risk patient with acute pulmonary thromboembolism.
Answers are grounded in this paper and cite their sources.
ECG T-wave inversions may signal right ventricular strain in pulmonary embolism; leaves open prospective validation beyond this single case.
ECG CORNERtoward the left, 90° away from the lead III, inscribing T inversion therein.Increased stimulation of the sympathetic nervous system due to pain, anxiety, and hypoxia can contribute to sinus tachycardia.• An obese diabetic female with DVT of the lower limbs suggests a prothrombotic milieu.Sudden-onset breathlessness in this situation raises suspicion of pulmonary thromboembolism.An elevated serum D-dimer level strongly supports this diagnosis, and CTPA provides confirmatory evidence. HistoryA 48-year-old obese diabetic female (random blood sugar 550 mg) with chest pain and breathlessness. Deep vein thrombosis (DVT) (both lower limbs).The following is the electrocardiogram (ECG) of the concerned case, presented in Figure 1. Findings o n ECg• Sinus tachycardia.• T inversion in leads II, III, aVF, and V1, V3-V6 (T vector = -45° on hexagonal lead system).• Clockwise rotation.• Low-voltage QRS over chest leads (<10 mm amplitude). rElEvant invEstigationsD-dimer was elevated (6230 ng/mL; normal, <550 ng/mL), and computed tomography pulmonary angiography (CTPA) confirmed pulmonary thromboembolism. CommEntsAcute pulmonary embolism (PE) usually causes right ventricular strain with its dilatation.There may be a shift of the T vector more
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DP Khaitan (2026) conducted a case report in Acute pulmonary thromboembolism and deep vein thrombosis (n=1). 12-lead Electrocardiogram and Computed Tomography Pulmonary Angiography (CTPA) was evaluated on ECG manifestations of acute pulmonary embolism. Acute pulmonary embolism in a 48-year-old female presented with D-dimer of 6230 ng/mL, sinus tachycardia, and T-wave inversions in leads II, III, aVF, V1, and V3-V6 (T vector -45°).
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