Key result
High cardiovascular risk factors paradoxically coincide with ~0% post-MI signs in Cretan men under 64.
Why the study?
This primary health care research project in Crete aimed to survey the cardiovascular risk profile of a defined low-risk population.
Cross-Sectional (n=445)
No
A cross-sectional survey in rural Crete revealed an absence of prior myocardial infarction in men <=63 years despite a high burden of traditional cardiovascular risk factors, potentially due to protective social and dietary factors such as olive oil consumption.
Answers are grounded in this paper and cite their sources.
High smoking and alcohol intake in this low-risk population may inform local screening; leaves open causal links to cardiovascular outcomes.
We have established a research project in primary health care in Crete with the aim of surveying the cardiovascular risk profile of a defined 'low-risk' population. The study population comprised all men and women aged 15-79 years in the village of Spili (n = 445); the overall attendance rate was 77% (greater than or equal to 82% in those aged 45 years and above). In this cross-sectional study we found a high (44%) prevalence of smoking in men aged 45-64 years as well as a high alcohol intake (48% drank greater than or equal to 210 g of pure alcohol every week). Furthermore, there was a high cholesterol level (6.2 mmol.l-1), and a high prevalence of hypertension and diabetes. Against this background it is somewhat surprising that we did not find any signs of post-myocardial infarction in Spili men aged 63 and under. It is possible that positive factors, i.e. the closely knit social networks, the low unemployment rate, the hard water, and some of the dietary habits, e.g. the high consumption of olive oil, may counter-balance the negative factors mentioned above. It is also possible that the low risk factors in the past explain the low incidence of myocardial infarction today, and that this will change in the years to come.
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Lindholm et al. (1992) conducted a cross-sectional in Ischaemic heart disease and cardiovascular risk factors (n=445). Cardiovascular risk factors (smoking, alcohol intake, high cholesterol, hypertension, diabetes) and protective lifestyle factors was evaluated on Signs of post-myocardial infarction in men aged 63 and under. High smoking (44%), alcohol intake (48% >=210 g/wk), and cholesterol (6.2 mmol/L) in Spili men were accompanied by 0% signs of post-MI in men aged <=63 years.
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