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Post-operative fistulas rank among the surgical complications with the greatest clinical and economic impact.They arise from the development of an abnormal communication between viscera or between a viscus and the skin leading to loss of gastrointestinal contents, sepsis and malnutrition.Incidence ranges from 3 % to 15 % after abdominal surgery and is higher in malnourished patients or those undergoing emergency procedures.Early diagnosis, based on clinical signs and high-resolution imaging, is crucial for therapeutic success.Management must combine sepsis source control, maintenance of fluid-electrolyte balance, individualized nutritional support and a timely choice between conservative treatment and surgical intervention.Minimally invasive techniques such as image-guided percutaneous drainage, biological sealants and endoscopic therapy have reduced the need for extensive re-operations.At the same time, multidisciplinary protocols add value to care by integrating surgeons, radiologists, nutritionists, stoma care nurses and psychologists.Despite progress, challenges persist, including case heterogeneity, scarcity of randomized clinical trials and lack of universally accepted guidelines.Understanding pathophysiology, risk factors and treatment options refines clinical decision-making, reduces morbidity and optimizes quality of life for affected patients.Insight into mechanisms involving ischemia, infection and technical failure of the anastomosis underpins preventive strategies such as optimizing blood supply, judicious suture use and appropriate antibiotic prophylaxis.Evidence-based protocols and well-trained teams are essential to lower incidence and improve outcomes.
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Ziviani et al. (2025) studied this question.
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