A Comprehensive Compilatory Clinical Review of Ayurvedic Therapeutic Approaches in Hypertension

Q: What is the clinical evidence from this study?

Study design: Review. Population: Hypertension (n=745). Intervention: Ayurvedic therapeutic approaches (herbal formulations, Panchakarma procedures, and Nidana Parivarjana) vs. Conventional antihypertensive therapy (Amlodipine, Losartan, Chlorthalidone) or comparative Ayurvedic regimens. Primary outcome: Systolic and diastolic blood pressure reduction (p=<0.001).

Q: What does this research mean for the field?

Ayurvedic interventions, including herbal formulations and Panchakarma therapies, significantly reduce systolic and diastolic blood pressure and improve clinical symptoms in patients with essential hypertension. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

Q: What question did this study set out to answer?

To critically review and analyze published Ayurvedic clinical studies, research articles, dissertations, and case reports on the management of hypertension.

Rajnikant Rohilla; Abhishek Thakur

doi:10.21760/jaims.11.9.52

October 27, 2026Journal of Ayurveda and Integrated Medical SciencesOpen Access

A Comprehensive Compilatory Clinical Review of Ayurvedic Therapeutic Approaches in Hypertension

View Full Paper

Ask AI

Bookmark

Share

Key result

Ayurvedic herbs and Panchakarma lower blood pressure and improve symptoms in essential hypertension.

P<0.001
n=745

Why the study?

Lifelong treatment, adverse effects, and poor compliance with antihypertensive medications have encouraged exploration of complementary therapeutic approaches, prompting a critical review of published Ayurvedic clinical studies, research articles, and case reports in hypertension management.

Do Ayurvedic therapeutic approaches (herbal formulations, Panchakarma procedures, and lifestyle modifications) reduce blood pressure and improve associated symptoms in patients with hypertension?

Key Points

To critically review and analyze published Ayurvedic clinical studies, research articles, dissertations, and case reports on the management of hypertension.
Reviewed literature comprising clinical studies, dissertation works, and case reports investigating Ayurvedic therapies for hypertension.
Assessed outcomes across multiple therapeutic modalities, including herbal formulations, Panchakarma procedures, and lifestyle modifications (Nidana Parivarjana).
Most reviewed studies reported reductions in systolic and diastolic blood pressure alongside improvements in related symptoms including headache, dizziness, insomnia, and anxiety.
Combinations of herbal formulations (such as Arjuna-based preparations) with Panchakarma procedures like Virechana and Basti, or with conventional medications, yielded superior outcomes compared to monotherapy.
Interventions generally showed favorable safety profiles across reviewed studies, with no significant adverse effects or clinically important biochemical abnormalities reported.

Structured PICO

Do Ayurvedic therapeutic approaches (herbal formulations, Panchakarma procedures, and lifestyle modifications) reduce blood pressure and improve associated symptoms in patients with hypertension?

P

Population

745 total patients aged 18–70 years with essential or resistant hypertension enrolled across 10 clinical studies and case reports conducted in India, followed for 4 to 24 weeks.

I

Intervention

Ayurvedic therapeutic approaches including Shamana (oral herbal and herbo-mineral formulations such as AVBJ powder, Chandraprabhavati, Punarnava Mandura, Sweta Parpati, Arjuna Vachadi Yoga, Arjunadi Ghanavati, Eclipta alba aqueous extract, polyherbal formulation TF-1, Tagaradi Churna, Sarpagandha Vati, Punarnavadi Kashaya, Trinpanchmool Kwath, Rudraksha Churna), Shodhana/Panchakarma procedures (Virechana Karma, Kala Basti, Abhyanga, Sarvanga Swedana, Matra Vasti), and Nidana Parivarjana (lifestyle and dietary modifications).

C

Comparator

Conventional antihypertensive therapy (amlodipine 5 mg once daily, losartan 50 mg once daily, chlorthalidone 12.5 mg once daily), alternative Ayurvedic regimens, or single-arm baseline comparisons across the reviewed studies.

O

Outcome

Systolic blood pressure (SBP) and diastolic blood pressure (DBP) reductionssurrogate

Main Result

p-value: p=<0.001

This compilatory clinical review suggests that Ayurvedic herbal formulations, Panchakarma procedures, and lifestyle modifications may safely reduce blood pressure and alleviate symptoms in essential hypertension, though larger, rigorous randomized controlled trials are needed.

Limitations

Small sample sizes
Short treatment duration
Methodological heterogeneity and heterogeneous study designs
Inadequate blinding
Insufficient long-term follow-up
Methodological heterogeneity across reviewed studies

Ask about this paper

Answers are grounded in this paper and cite their sources.

Implication

Hypothesis-generating for Ayurvedic approaches in hypertension; rigorous RCTs required before clinical adoption.

Abstract

Background: Hypertension is one of the leading non-communicable diseases worldwide and a major risk factor for cardiovascular, cerebrovascular, and renal complications. Although effective antihypertensive medications are available, lifelong treatment, adverse effects, and poor compliance have encouraged exploration of complementary therapeutic approaches. Ayurveda offers a holistic approach to hypertension through Dosha-based management, lifestyle modification (Nidana Parivarjana), Shamana, and Shodhana therapies. Aim: To critically review and analyze the published Ayurvedic clinical studies, research articles, and case reports related to the management of hypertension. Materials and Methods: Several dissertations works and case reports in the field of hypertension were reviewed in detail. The review focused on the importance of various modified interventions and the outcomes achieved during the clinical trials, which have been summarized accordingly.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Rohilla et al. (2026) conducted a review in Hypertension (n=745). Ayurvedic therapeutic approaches (herbal formulations, Panchakarma procedures, and Nidana Parivarjana) vs. Conventional antihypertensive therapy (Amlodipine, Losartan, Chlorthalidone) or comparative Ayurvedic regimens was evaluated on Systolic and diastolic blood pressure reduction (p=<0.001).

synapsesocial.com/papers/6aee6bd871a7594806220c27 https://doi.org/10.21760/jaims.11.9.52

View Full Paper

Ask AI

Bookmark

Share

A Comprehensive Compilatory Clinical Review of Ayurvedic Therapeutic Approaches in Hypertension

Key Points

Structured PICO

Main Result

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

A Comprehensive Compilatory Clinical Review of Ayurvedic Therapeutic Approaches in Hypertension

Key Points

Structured PICO

Main Result

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading