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Objective: This report details an atypical presentation of hand, foot, and mouth disease (HFMD) in a 35-year-old female. Method: The patient presented with acute unilateral painless central vision loss with recent coryzal symptoms and a vesicular rash on her hands and feet. Investigation revealed retinal pigment epithelium (RPE) disruption and subretinal thickening infero-nasally to the fovea. Results: Orbital corticosteroids were successfully administered. The investigative and management approach has been compared to that of similar cases available in the literature. Conclusion: This report summarises a case report and a review of available literature on HFMD associated maculopathy, providing an overview on the condition.
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Quiney et al. (2026) studied this question.
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