Association between the severity of anatomical damage to the coronary arteries and clinical indicators and Holter electrocardiogram monitoring indicators

Aim To determine the association between the severity of anatomical damage to the coronary arteries and clinical and Holter electrocardiogram monitoring results. Material and methods A total of 60 patients were examined; the mean age was 61.67 ± 7.72 years. All patients had stage II hypertension and chronic ischemic heart disease, with or without frequent ventricular premature beats. The nature of the anatomical lesions of the coronary arteries was determined for all patients based on data from coronary ventriculography, which was performed in 3 groups: group 1—all examined patients (n = 60), Group 2 — patients with frequent ventricular extrasystoles (n = 30), Group 3 — patients without frequent ventricular extrasystoles (n = 30) with chronic ischemic heart disease. Results In patients with chronic ischemic heart disease, frequent ventricular premature beats (a sign of myocardial electrical instability) are associated with more severe atherosclerotic multivessel disease of the coronary arteries (56.7% of cases), the development of subocclusions and occlusions (100% of cases), as well as with a significantly higher total severity score for anatomical lesions of the coronary arteries based on coronary ventriculography (an average of 5.3 points). Conclusions A high total score for the severity of anatomical coronary artery disease and more severe anatomical coronary artery disease in patients with chronic coronary artery disease are associated with male gender, a higher functional class of angina, a longer history of ventricular extrasystoles, the presence of allorhythmia, and an increase in the number of supraventricular and ventricular extrasystoles per day as determined by Holter electrocardiogram monitoring.