Key result
Multimodal therapy with thrombolysis stabilizes canine aortic thrombosis and resolves hepatic lesions at 7 months.
Case Report (n=1)
This veterinary case report demonstrates that life-threatening aortic thrombosis and septic complications following hepatic tumor embolization in a dog can be successfully managed with timely multimodal therapy, including thrombolysis.
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This outcome suggests potential for survival in severe post-procedural complications; leaves open optimal protocols for canine hepatic embolization patients.
This report details the case of an 8-year-old neutered male Shiba Inu who developed septic peritonitis following transarterial embolization of a hepatic tumor. After surgical management of the hepatic abscess and peritonitis, the dog experienced several severe complications, including aortic thrombosis with pelvic limb neurological deficits, acute kidney injury, coagulopathy, and marked hypoalbuminemia. Intensive care included hemodynamic and surgical stabilization, antimicrobial therapy, analgesia, nutritional support, and a combination of antithrombotic and thrombolytic treatments. The clinical course was characterized by progressive stabilization of sepsis and the hepatic lesion, partial restoration of aortic blood flow, neurological improvement, and gradual recovery of renal function. Seven months after discharge, the dog remained clinically stable, with resolution of the hepatic lesion and persistent stability of the aortic thrombus on ultrasonography. This case demonstrates that life-threatening aortic thrombosis and septic complications following hepatic embolization can be successfully managed with timely and multimodal therapy, including thrombolysis.
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Déchelette et al. (2026) conducted a case report in Septic peritonitis and aortic thrombosis following transarterial embolization of a hepatic tumor (n=1). Multimodal intensive care including surgical stabilization, antimicrobials, analgesia, nutritional support, and antithrombotic/thrombolytic therapy was evaluated on Clinical stabilization, hepatic lesion resolution, and aortic thrombus stability. Multimodal therapy with thrombolysis in 1 dog (8 years old) resulted in hepatic lesion resolution and stable aortic thrombus at 7 months post-discharge.
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