Cefazolin vs Cloxacillin for Methicillin-Susceptible S aureus Bacteremia: A Meta-Analysis of 2 Randomized Clinical Trials

Todd Campbell Lee; Steven Tong; Joshua Saul Davis; Arthur M. Albuquerque; Matthew Pellan Cheng; Jacob Dye; Nesrin Ghanem‐Zoubi; Anna L. Goodman; Nynke G L Jager; Achim J. Kaasch; Ilse J.E. Kouijzer; David Chien Lye; Alistair R. D. McLean; Brendan Joseph McMullan; David L. Paterson; Connor J. Prosty; Jay Roberts; Pierre Tattevin; Jonas Tverring; Dafna Yahav; Emily Gibson McDonald

doi:10.1001/jamanetworkopen.2026.43836

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Abstract

This bayesian meta-analysis of 2 randomized clinical trials synthesizes mortality and safety outcomes associated with cloxacillin vs cefazolin for treatment of methicillin-susceptible S aureus bacteremia.

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Lee et al. (2026) studied this question.

synapsesocial.com/papers/6af7f9e3a3236dc65aee5df7 https://doi.org/10.1001/jamanetworkopen.2026.43836

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Cefazolin vs Cloxacillin for Methicillin-Susceptible S aureus Bacteremia: A Meta-Analysis of 2 Randomized Clinical Trials

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Cefazolin vs Cloxacillin for Methicillin-Susceptible S aureus Bacteremia: A Meta-Analysis of 2 Randomized Clinical Trials

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Abstract

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