Key result
Higher Framingham Risk Score links to significantly lower exercise capacity and shorter treadmill duration.
Why the study?
The American Heart Association recommends predicting the risk of cardiovascular disease events using clinical and biochemical parameters, and the Framingham risk score estimates 10-year cardiovascular risk. This study aimed to estimate cardiovascular disease risk among urban adults using the Framingham score and evaluate its association with treadmill test parameters.
Does the 10-year Framingham Risk Score correlate with treadmill exercise test performance parameters in urban adults?
Cross-Sectional (n=120)
Single-blind
No
Does the 10-year Framingham Risk Score correlate with treadmill exercise test performance parameters in urban adults?
Higher Framingham risk scores are significantly associated with poorer treadmill exercise performance (lower METS, maximum heart rate, and test duration) among urban Indian adults.
Answers are grounded in this paper and cite their sources.
Higher Framingham scores associated with poorer treadmill performance; hypothesis-generating for combined screening, needs prospective validation.
Background: The American Heart Association recommends predicting risk of Cardiovascular Disease Events; they rely on clinical and biochemical parameters. Framingham risk score is used to estimate 10-year cardiovascular risk. This study aimed to estimate cardiovascular disease risk using the Framingham score and its association with treadmill test. Methods: A cross-sectional study was conducted among 120 adults attending the Master Health Check-up Department at KMCH, Coimbatore, India. Adults were categorized into low (<10%), intermediate (10-20%), and high (>20%) risk. Treadmill test parameters, including metabolic equivalents (METS), maximum heart rate achieved, and duration, were recorded for analysis. Data was analyzed using IBM SPSS Statistics version 32. Descriptive statistics, Spearman’s rank correlation coefficient, and Kruskal-Wallis tests were performed. Results: Among 120 adults, 91 (75.8%) were low, 26(21.7%) as intermediate, and 3 (2.5%) as high risk. Framingham Risk score demonstrated negative correlations with METS achieved (ρ = -0.635, p<0.001), maximum heart rate (ρ = -0.567, p<0.001), and treadmill test duration (ρ = -0.670, p<0.001). Significant differences across treadmill test parameters were observed across Framingham risk categories (p<0.001). Conclusion: Higher Framingham risk scores were associated with poorer tread mill performance. Combining cardiovascular risk assessment with treadmill exercise testing may facilitate identification of cardiovascular risk.
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S et al. (2026) conducted a cross-sectional in Cardiovascular disease risk assessment in asymptomatic urban adults (n=120). Framingham Risk Score (10-year cardiovascular disease risk) vs. Low (<10%), intermediate (10-20%), and high (>20%) Framingham risk categories was evaluated on Exercise capacity (METS achieved) on symptom-limited Bruce protocol treadmill test (Spearman's rho -0.635 (Linear regression beta -0.553), 95% CI -0.202 to -0.115, p=<0.001). Higher Framingham Risk Scores correlated with lower treadmill exercise capacity in METS and shorter test duration in urban adults.
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