Key result
Simultaneous bilateral lung transplantation, pericardiectomy, and tricuspid valve replacement successfully managed a 37-year-old woman with cystic fibrosis and complex right-sided cardiac disease.
Why the study?
This case report describes the management of pre-existing constrictive pericarditis and severe tricuspid regurgitation in a woman with cystic fibrosis listed for high-emergency bilateral lung transplantation.
Case Report (n=1)
No
Answers are grounded in this paper and cite their sources.
Complex right-sided cardiac disease (constrictive pericarditis and severe tricuspid regurgitation) can be successfully managed simultaneously with bilateral lung transplantation in selected patients at high-volume centers.
This case report describes the management of pre-existing constrictive pericarditis and severe tricuspid regurgitation in a 37-year-old woman with cystic fibrosis listed for high-emergency bilateral lung transplantation. Preoperative assessment showed constrictive hemodynamics, pulmonary hypertension, and pericardial calcifications. She underwent simultaneous bilateral lung transplantation, pericardiectomy, and tricuspid valve replacement using tailored extracorporeal support. Histopathology confirmed chronic fibro-calcific constrictive pericarditis. This case suggests that complex right-sided cardiac disease should not automatically preclude lung transplantation in selected patients managed in high-volume centres.
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Lajoye et al. (2026) conducted a case report in Cystic fibrosis with pre-existing constrictive pericarditis and severe tricuspid regurgitation (n=1). Simultaneous bilateral lung transplantation, pericardiectomy, and tricuspid valve replacement was evaluated. Simultaneous bilateral lung transplantation, pericardiectomy, and tricuspid valve replacement successfully managed a 37-year-old woman with cystic fibrosis and complex right-sided cardiac disease.
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