Key result
Frailty theory and mediation models provide key frameworks to reassess hypertension-frailty links in older adults.
Why the study?
This letter to the editor responds to a study by Maheshwari and Basu on the association between hypertension and frailty among middle-aged and older adults in India.
Population
Middle-aged and older adults in India
Design
Letter to the editor
Answers are grounded in this paper and cite their sources.
Methodological alignment of mediation models with frailty biology is required to avoid bias; leaves open causal inferences from cross-sectional data.
Dear Editor,We read with considerable interest the article by Maheshwari and Basu [1], which examined the association between hypertension and frailty among middle-aged and older adults in India us...
No takes yet. Share an insight, caveat, or question.
Pratiwi et al. (2026) studied this question. Statistical mediation models and frailty theory offer critical perspectives for re-evaluating the association between hypertension and frailty in middle-aged and older Indian adults.
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