Key result
Cardiac rehabilitation after TAVI improves exercise capacity but lacks randomized evidence for clinical events.
Why the study?
Although TAVI relieves valvular obstruction, recovery of mobility, independence, exercise capacity, and health-related quality of life remains incomplete in many patients.
Does cardiac rehabilitation improve multidomain recovery, peak oxygen uptake, and clinical outcomes in patients after transcatheter aortic valve implantation (TAVI)?
Does cardiac rehabilitation improve multidomain recovery, peak oxygen uptake, and clinical outcomes in patients after transcatheter aortic valve implantation (TAVI)?
This narrative review highlights that while exercise-based cardiac rehabilitation after TAVI shows a signal for improving peak oxygen uptake, evidence for hard clinical outcomes is lacking and a personalized, multidomain recovery framework is needed.
Answers are grounded in this paper and cite their sources.
Variable post-TAVI effects warrant cautious implementation; leaves open definitive randomized trials on multidomain strategies.
Transcatheter aortic valve implantation (TAVI) relieves valvular obstruction, but recovery of mobility, independence, exercise capacity, and health-related quality of life remains incomplete in many patients. This narrative review critically appraises cardiac rehabilitation (CR) after TAVI and proposes a needs-guided recovery framework. A search of MEDLINE, trial registries, guidelines, and citation networks through 4 September 2026 identified small, heterogeneous randomised trials and observational and implementation studies. Exercise-based interventions provide the most consistent, although imprecise, signal for increased peak oxygen uptake; effects on walking capacity, lower-extremity performance, disability, and quality of life are variable. No randomised trial has demonstrated reduced rehospitalisation or mortality, and favourable cohort associations remain susceptible to referral, survival, and healthy-participant bias. Contemporary guidelines support comprehensive CR but do not define a universal initiation time, exercise dose, or TAVI-specific safety thresholds. We propose proactive referral, confirmation of medical readiness, and assessment of cardiovascular stability, physical performance, frailty, nutrition, cognition, mood, falls risk, and contextual barriers to guide individualised exercise, nutritional, behavioural, and self-management interventions. Delivery, supervision, progression, and maintenance should match risk and access. Pragmatic trials should establish durability, safety, disability-free survival, healthcare utilisation, equity, and cost-effectiveness.
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Tsigkas et al. (2026) conducted a review in Patients undergoing transcatheter aortic valve implantation (TAVI). Cardiac rehabilitation was evaluated. Cardiac rehabilitation after TAVI shows a consistent signal for increased exercise capacity, though 0 randomised trials have demonstrated reduced rehospitalisation or mortality.
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