What question did this study set out to answer?

To identify and address scientific objections related to the DQIS framework for academic validation.

May 1, 2026Open Access

DQIS — Register of Scientific Objections v3.0

Key Points

To identify and address scientific objections related to the DQIS framework for academic validation.
Document includes 6 objections addressing mathematical and biological analyses.
Empirical grounding and statistical methods used to resolve objections.
Defensible responses formulated for each objection based on literature data.
Six objections were addressed, each with detailed analyses and responses.
Specific resolutions include parameter grounding, statistical independence validation, and temporal integration discussions.

Abstract

Supplementary document to the DQIS framework (Zenodo DOI: 10. 5281/zenodo. 19855263). Register of scientific objections identified during preparation for academic validation of the DQIS framework — Distributed Quantum-Inspired Immune Surveillance. For each objection: precise formulation, severity assessment, mathematical and biological analysis, empirical data from the literature, and defensible response. Version 3. 0 — 6 objections addressed: O1 — Empirical grounding of parameter pᵢ (with per-channel proxies from literature + technical feasibility of sensors) O2 — Statistical independence of channels (resolved with balanced group quorum) O3 — Selective pressure at population scale (explicit calculation + τᵢ update mechanism) O4 — Channel T-ε: reachability of pᵢ = 0. 01 O5 — DQIS-J: number of paediatric procedures O6 — T-γ* temporal criterion (>30 min) vs T-lymphocyte contact time (resolved with NFAT-like temporal integration) Not a peer-reviewed publication. Prior art deposit.

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