August 5, 2025PolymersOpen Access

Polyethylenimine Carriers for Drug and Gene Delivery

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Authors

AIAhmed IsmailThe University of Texas at Tyler SCShih‐Feng ChouThe University of Texas at Tyler

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Implication

Review highlights biocompatibility and efficiency of polyethylenimine carriers for drug delivery and gene delivery, suggesting pathways for clinical use.

Key Points

Polyethylenimine (PEI) is a promising carrier for drug and gene delivery due to its high density of amine groups.
The review covers various forms of PEI carriers, including nanoparticles and hydrogels, focusing on their applications.
Factors like molecular weight and branching degrees significantly affect the biocompatibility and transfection efficiency of PEI carriers.
Despite its potential, PEI's clinical use is limited by cytotoxicity and stability challenges in biological environments.

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Ismail et al. (2025) studied this question.

synapsesocial.com/papers/689522009f4f1c896c428ecd https://doi.org/10.3390/polym17152150

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Implication

Review highlights biocompatibility and efficiency of polyethylenimine carriers for drug delivery and gene delivery, suggesting pathways for clinical use.

Polyethylenimine Carriers for Drug and Gene Delivery

Discussion

Member takes

Implication

Key Points

Cite This Study

Polyethylenimine Carriers for Drug and Gene Delivery

Discussion

Member takes

Implication

Key Points

Cite This Study

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