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August 7, 2025International Journal of Molecular SciencesOpen Access

Biomarkers of Metabolism and Inflammation in Individuals with Obesity and Normal Weight: A Comparative Analysis Exploring Sex Differences

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Authors

EGEveline GartJSJessica SnabelJJJelle C. B. C. de Jong

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Overview

Comparative analysis of biomarkers in obesity reveals sex differences in inflammation and metabolism.

Key Points

  • Individuals with obesity had elevated inflammation biomarkers compared to those of normal weight.
  • More than 90 blood-based biomarkers were analyzed using ELISA and multiplex methods across BMI groups.
  • Sex differences in biomarker levels were observed within both normal weight and obese individuals.
  • The comprehensive dataset serves as a helpful reference for researchers to choose appropriate biomarkers.

Cite This Study

Gart et al. (2025) studied this question.

synapsesocial.com/papers/689522129f4f1c896c429bdfhttps://doi.org/10.3390/ijms26157576
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Also Consider

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  1. 1Sex-biased plasma inflammatory protein profile in obesity2026 · 1 citations
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  3. 3Peripheral Blood Mononuclear Cells Oxidative Stress and Plasma Inflammatory Biomarkers in Adults with Normal Weight, Overweight and Obesity2021 · 27 citations
  4. 4Dynamics of Serum Inflammatory Markers and Adipokines in Patients: Implications for Monitoring Abnormal Body Weight: Preliminary Research2024 · 6 citations
  5. 5Sex-Specific Effects of Obesity Severity on Circulating Inflammatory Mediators and Immune Cell Gene Expression2026