August 6, 2025Open Access

A Super-Aged Microminipig Model for the Development of Health Foods for the Elderly: A Pilot Study on the Administration of Sweet Potato Petiole and Leaf Powder

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Discussion

Pilot study shows polyphenol-rich diet improves gut microbiota in aged microminipigs, suggesting potential for health food evaluation.

The study established a super-aged microminipig model to assess health foods aimed at the elderly.
Long-term administration of sweet potato petiole and leaf powder increased specific gut microbiota genera.
Analysis indicated significant differences in 77 metabolic enzymes related to the diet, affecting 27 pathways.
The findings support using this microminipig model for evaluating drugs and health foods for elderly populations.

Sugai et al. (2025) studied this question.

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