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July 14, 2025Frontiers in ImmunologyOpen Access

Research progress on the interaction between glucose metabolic reprogramming and lactylation in tumors

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Authors

YYYi YangYWYi‐Long WuHCHui Chen

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Overview

This review demonstrates how glucose metabolic reprogramming influences lactylation in tumors, suggesting implications for tumor progression and immune evasion.

Key Points

  • Glucose metabolic reprogramming enhances glycolysis and lactate accumulation in tumor cells.
  • Lactylation, a post-translational modification, affects protein function and gene expression.
  • The interplay between glucose reprogramming and lactylation contributes to immune evasion in tumors.
  • Understanding these mechanisms could lead to new therapeutic targets in cancer treatment.

Cite This Study

Yang et al. (2025) studied this question.

synapsesocial.com/papers/689a02afe6551bb0af8cc063https://doi.org/10.3389/fimmu.2025.1595162
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